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Daniel James George, MD, FASCO, a medical oncologist at Duke Cancer Institute and trial investigator, explained the clinical purpose of this design: “The schedule was selected specifically to maintain efficacy but allow for mitigation of the cumulative side effects that the regimen could cause.” This structured therapeutic pause prevents the compound from continuously accumulating in healthy somatic tissues

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For vegetarians, fortified foods like breakfast cereals, plant-based milk, and nutritional yeast can provide B12

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