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If folate deficiency is suspected, it is reasonable to give oral folic acid (0.4 – 1 mg/day) without doing laboratory investigation for deficiency at least until the hemoglobin and mean corpuscular volume normalizes (or longer if the underlying cause cannot be eliminated)

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Clozapine is known to potentially cause serious side effects, including leukopenia (low white blood cell count) and neutropenia (low neutrophil count), which can increase the risk of infections