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Receptor Supersensitivity Blockade In the landmark 1997 Sikiric study published in Biological Psychiatry (PMID: 9547930), mice pretreated with haloperidol (a dopamine antagonist) developed behavioral supersensitivity to amphetamine challenge

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These cells have an abnormal rounding cell structure, with some cultures displaying bright lipid nodules but they lack the clearly demarcated polygonal shape of GF-HLCs or PHHs