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Recent solution NMR structural studies have provided detailed molecular models of the p53 transactivation domain in complex with both the FOXO4 forkhead domain and FOXO4-DRI, advancing understanding of the precise molecular interactions that enable selective senescent cell targeting in research applications

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All experiments were performed at 25 °C in a buffer solution containing 20 mM HEPES (pH 7.0), 150 mM NaCl, and 1 mM DTT

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